The latest Barings Investment Barometer has revealed 31 per cent of financial advisers questioned believe a stagnant or declining GDP will be the main challenge to investment growth this year.
This was up 11 per cent on the previous study from Barings Asset Management, which was published in September, demonstrating that intermediaries are more concerned about this issue than they were.
There was also a 12 per cent climb in the number of intermediaries that envisage a rise in inflation over the next three years, with 55 per cent of respondents convinced the UK will witness an increase in inflation.
As the study stated, an "unsurprising" 80 per cent of financial advisers revealed their clients were worried about the impact this would have on their cash investments.
While confidence in the UK economy remains fragile, it appears sentiment in both the eurozone and Chinese economies has climbed.
Some 77 per cent of intermediaries surveyed admitted they were concerned by the Eurozone crisis, down from 89 per cent in the previous barometer.
A further 37 per cent of respondents expressed worry over the slow down in growth in China, which was far lower than the 53 per cent of advisers who said the same in the previous study.
Head of UK retail distribution at Barings Rod Aldridge said: "As we enter 2013, macro-economic concerns continue to be at the forefront of financial advisers' minds, with the UK economy proving one of the biggest challenges."
Projections from the International Monetary Fund indicate the European economy, excluding the UK, will expand just 0.2 per cent in 2013.
However, the UK is expected to witness slightly better growth of 1.1 per cent by the end of the year.
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